Von Willebrand’s Disease is a common hereditary coagulation abnormality caused by a qualitative or quantitative deficiency of von Willebrand factor (vWF). Von Willebrand factor (vWF) is a protein that is essential for platelet adhesion.
There are three forms of VWD: inherited, acquired and pseudo or platelet type. There are three types of inherited VWD: Type I, Type II and Type III. Platelet type VWD is also an inherited condition.
VWD Type I is more common than Types II and III, and those that have it are typically asymptomatic or may experience mild symptoms such as nosebleeds, although there may be severe symptoms in some cases.